Name

Action

Dose

mg/Kg

Duration

min

Blood Pressure

Side effects

Contraindications

Suxamethonium

Ultra short acting depolarising neuromuscular blocker

1 -2

5 - 10

›

Muscle pains

Bradycardia

Increase plasma K

Absent PsChE

Hyperkalaemia

Burns

Myotonia

Gallamine

Synthetic non depolarising neuromuscular blocker

2

35

›

Tachycardia

Renal Failure

Tubocurarine

Non depolarising neuromuscular blocker

0.5

45

fl

Hypotension; histamine release

Myasthenia

Shock

Atracurium

Medium long acting non depolarising neuromuscular blocker

0.5

25

—

Histamine release in high doses

—

Pancuronium

Non depolarising neuromuscular blocker

0.08

40

›

Hypotension

Myasthenia

Vecuronium

Medium long acting non depolarising neuromuscular blocker

0.08

25

—

—

—

Alcuronium

non depolarising neuromuscular blocker

0.25

35

fl

Histamine release

Myasthenia

 

      Reversal

      •    Depolarising agents: cholinesterase inhibiting drug (eg neostigmine) preceded by atropine