TEMPERATURE & ADULT PERFUSION.. 1

Relationship of core temperature to: nasopharyngeal; rectal; toe; mixed venous; oesophageal; tympanic  1

Temperature measurement of adult patients on CPB.. 2

Effect of pharmacological intervention on core temp. 3

 

TEMPERATURE & ADULT PERFUSION

 

 

Cardiac Indexes with hypothermia

 

Temperature (°C)

Cardiac index [l/min/m2]

 

34—37

2.4

 

30—34

2.0

 

25—30

1.8

 

20—25

1.5

 

<18

1

 

1.                  Effects of hypothermia on biochemical reactions

a)                  Q10 » 2

i)                    For each 10° drop in temperature, the rate of metabolic rate or O2 consumption is roughly halved

 

2.                  Hypothermia permits the use of lower blood flows

a)                  Reduced blood trauma

b)                  Permitting longer safe CPB

i)                    Emergency pump shut off

c)                  Reduced blood return to heart

i)                    Reduced non coronary collateral flow

ii)                  Drier operative field

d)                  Cooler heart

e)                  Reduced myocardial ischaemia

f)                    

 

Relationship of core temperature to: nasopharyngeal; rectal; toe; mixed venous; oesophageal; tympanic

·       Note that the high blood flow to the upper body will cause preferential changes to temperature here ie may have warm head but lower body is inadequately rewarmed

 

1.                  CORE temperature

a)                  Monitors the well perfused organs

 

2.                  SHELL [peripheral] temperature

a)                  Monitors poorly perfused muscle-fat tissues

 

3.                  Nasopharyngeal

a)                  Good estimate of brain temperature [roughly equivalent to core]

b)                  May be influenced by aortic temp?

c)                  Adequacy of rewarming at 37°C

 

4.                  Oesophageal

a)                  Estimate of myocardial temperature

b)                  Affected by cold slush etc in mediastinum

c)                  Must be positioned below tracheal bifurcation

d)                  Adequacy of rewarming at 35°C

 

5.                  Mixed venous

a)                  Measure of average body temperature

 

6.                  Tympanic

a)                  Good estimate of brain temperature

b)                  Not affected by major vessel temperatures

c)                  Danger of penetrating ear drum

d)                  Adequacy of rewarming at 37°C

 

7.                  Rectal

a)                  Shell temperature

b)                  Adequacy of rewarming at 35°C

 

8.                  Toe

a)                  Indication of peripheral temperature

b)                  Adequacy of rewarming at 30°C

c)                  Use in paediatrics

d)                  A widening gap between core  & peripheral temp indicates vasoconstriction

 

9.                  Myocardial

a)                  Needle inserted into interventricular septum

b)                  Should be < 15°C during cold cardioplegia

 

Temperature measurement of adult patients on CPB

1.                  During Cooling

a)                  Target is brain (organ most likely to receive most benefit from hypothermic protection)

b)                  Nasopharyngeal, oesophageal and tympanic membrane give good estimates of brain temperature

c)                  Mixed venous blood temperature gives average body temperature

d)                  Reduction to 28°C during routine CPB:

i)                    Reduced gradient between cooled heart & surroundings

ii)                  Can reduce flow rate, reducing collateral return to heart while still meeting the metabolic needs of the organs

iii)                 Safe arrest of 10-12 minutes if required

 

2.                  During Rewarming

a)                  Target is a normothermic patient at end of CPB

b)                  Both temperature & time dependent

c)                  Rebound hypothermia (afterdrop) following CPB due to deficit in heat return; may be tackled by vasodilators to promote a more uniform rewarming

d)                  Concerns of too rapid rewarming

i)                    GME

ii)                  vasoconstriction to brain with increased brain metabolism

e)                  Concerns of excessive temperature

i)                    > 42°C associated with blood damage

ii)                  Monitor via oxygenator outlet blood temperature

                                                                     

Effect of pharmacological intervention on core temp

·       Often have a deficit in heat return during rewarming leading to ‘afterdrop’ in temperature following termination of CPB

·       Rewarming is associated with large gradients between shell and core temperatures due to distribution of warm blood to well perfused core organs and reduced flow to peripheral organs due to vasoconstriction

·      Use of vasodilators during CPB rewarming promotes a more uniform rewarming thereby reducing incidence of afterdrop and hastening rewarming

 

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